Ngwa ọhụrụ nke phenylmethylamino acid—ihe ọhụrụ dị ịrịba ama n'ịkwalite ọganihu sayensị na teknụzụ na mmepe ahụike.

Na-adịbeghị anya, nnyocha naBenzylamino acid(Benzylation nke Amino Acids) adọtala nlebara anya zuru ebe niile. Benzylamino acid bụ usoro njikọ kemịkalụ, nke nwere ike nweta mgbanwe ọrụ site na iwebata otu benzyl n'ime ụmụ irighiri amino acid, ma nwee atụmanya ngwa ngwa. Amino acid bụ ihe ndị bụ isi na-ewu ụlọ protein, na ihe onwunwe ha na nhazi ha dị mkpa maka ọrụ nke protein. Site na iwebata otu benzyl, a ga-agbanwe akụrụngwa physicochemical nke mkpụrụ ndụ amino acid, si otú ahụ gbasaa ngwa ya na ngalaba ọgwụ, sayensị ihe onwunwe na njikọ organic.

N'ihe gbasara ọgwụ, a na-eji nyocha nke phenylmethyl amino acid mee ihe n'ọtụtụ ebe na nchịkọta ọgwụ. Ikike ya iwebata ndị otu benzyl na-enye ụmụ irighiri ọgwụ ọgwụ nwere usoro kwụsiri ike yana ohere iji meziwanye nnabata ha. Enwere ike imezi hydrophilicity na lipid solubility nke mkpụrụ ndụ ọgwụ site na iwebata otu benzyl, si otú ahụ meziwanye ọrụ ọgwụ ha na bioavailability. Nke a na-enye ohere ndị ọzọ maka ịmepụta ọgwụ ọhụrụ ma na-akwalite mmepụta ihe ọhụrụ na mmepe na ngalaba ọgwụ. Na mgbakwunye, phenylmethylamic acid nwekwara ọtụtụ ngwa nwere ike na ngalaba sayensị ihe.

Site n'ịchịkwa ọnọdụ njikọ, enwere ike ịkwadebe ihe polymer nwere ọrụ ụfọdụ. Ntinye nke otu benzyl nwere ike gbanwee ọrụ elu na ihe eji arụ ọrụ, si otú a na-emeziwanye arụmọrụ na ọrụ nke ihe. Nke a nwere mmetụta dị mkpa maka mmepe nke ubi dịka ihe batrị, ihe mmetụta na sensọ. Na mgbakwunye, mmepe nke p-benzyl amino acid usoro na-arụkwa ọrụ dị mkpa na njikọ organic. N'iji usoro a, ndị na-eme nchọpụta nwere ike ịgbanwe kpọmkwem nhazi nke mkpụrụ ndụ amino acid ka ha mejupụta ogige organic na ọrụ a kapịrị ọnụ, dị ka etiti ọgwụ na ụmụ irighiri ihe na-arụ ọrụ. Nke a na-enye ikpo okwu sara mbara maka kemịkalụ sịntetik organic ma na-akwalite n'ihu mmepe nke kemịkalụ organic.

Ka ọ dị ugbu a, a na-eme nchọpụta dị mkpa na nyocha nke p-phenylmethylamino acid. N'otu aka ahụ, n'ihe gbasara usoro njikọ, ndị na-eme nchọpụta na-eme ka ọnọdụ mmeghachi omume na-eme ka ọ dịkwuo mma mgbe niile na usoro ihe na-eme ka ọ dịkwuo mma iji meziwanye mmeghachi omume mmeghachi omume na selectivity. N'aka nke ọzọ, n'ihe gbasara mpaghara ngwa, a na-eji usoro phenylmethylamino acid mee ihe n'ọtụtụ ebe na nchọpụta ọgwụ na sayensị ihe onwunwe, ma nweta ọtụtụ ihe dị mkpa. N'okwu, nyocha na ntinye nke p-phenylmethylamino acid ga-enye aka dị mma na mmepe nke sayensị na nkà na ụzụ. Ngwa ọhụrụ nke usoro a ọ bụghị nanị na-akwalite mmepe nke ngalaba ọgwụ, kamakwa ọ na-eweta ọganihu ọhụrụ na ihe ọhụrụ na ngalaba nke sayensị ihe na njikọ organic. A kwenyere na site na mgbalị nke ndị nchọpụta ndị ọzọ, ntinye nke phenylmethylamino acid ga-egosi atụmanya sara mbara n'ọdịnihu.